Anti-SMG1 (aa 2300-2350) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

Synthetic peptide corresponding to a region between residues 2300 and 2350 of Human Smg1 (Q96QV0).

Conjugate

Application Notes

IHC-P: 1:100-1:500

Alternative Names

SMG1; smg-1 homolog, phosphatidylinositol 3-kinase-related kinase (C. elegans); serine/threonine-protein kinase SMG1; ATX; KIAA0421; LIP; phosphatidylinositol 3 kinase related kinase; ATX; hSMG1; Lambda interacting protein; Lambda/iota protein kinase C-interacting protein; LIP; phosphatidylinositol 3 kinase -related protein kinase; phosphatidylinositol 3 kinase related kinase; PI-3-kinase-related kinase SMG-1; OTTHUMP00000234388; lambda-interacting protein; PI-3-kinase-related kinase SMG-1; phosphatidylinositol 3-kinase-related kinase; lambda/iota protein kinase C-interacting protein; phosphatidylinositol 3-kinase-related protein kinase; SMG1 homolog, phosphatidylinositol 3-kinase-related kinase; 61E3.4;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a protein involved in nonsense-mediated mRNA decay (NMD) as part of the mRNA surveillance complex. The protein has kinase activity and is thought to function in NMD by phosphorylating the regulator of nonsense transcripts 1 protein. Alternative spliced transcript variants have been described, but their full-length natures have not been determined.

Pathway

Metabolism, organism-specific biosystem; Metabolism of RNA, organism-specific biosystem; Metabolism of mRNA, organism-specific biosystem; Nonsense Mediated Decay Enhanced by the Exon Junction Complex, organism-specific biosystem; Nonsense-Mediated Decay, organism-specific biosystem; mRNA surveillance pathway, organism-specific biosystem; mRNA surveillance pathway, conserved biosystem;