Specifications
Immunogen
Full length human SLC7A7 protein (AAH03062. 1).
Applications
Application Notes
WB: 1:500-1:1000
Target
Alternative Names
SLC7A7; solute carrier family 7 (amino acid transporter light chain, y+L system), member 7; LPI; Y+L amino acid transporter 1; y+LAT 1; LAT3; LPI; Monocyte amino acid permease 2; MOP-2; MOP2; SLC7A 7; Slc7a7; Solute carrier family 7 (cationic amino acid transporter, y+ system), member 7; Solute carrier family 7 member 7; y(+)L type amino acid transporter 1; y(+)L-type amino acid transporter 1; Y+L amino acid transporter 1; y+LAT-1; Y+LAT1; YLAT1_HUMAN; monocyte amino acid permease 2; y(+)L-type amino acid transporter 1; solute carrier family 7 (cationic amino acid transporter, y+ system), member 7; LAT3; MOP-2; Y+LAT1; y+LAT-1;
Product Background
Antigen Description
The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants.
Pathway
Amino acid transport across the plasma membrane, organism-specific biosystem; Basigin interactions, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem; Protein digestion and absorption, conserved biosystem; SLC-mediated transmembrane transport, organism-specific biosystem; Transmembrane transport of small molecules, organism-specific biosys
Citations
Publication ()
Have you cited CABT-BL5709 in a publication?
Let us know and earn a reward for your research.