Specifications
Immunogen
SLC7A7 (NP_003973, 462 aa ~ 512 aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Alternative Names
solute carrier family 7 (cationic amino acid transporter, y+ system), member 7; Y+LAT1; y+LAT-1; y(+)L-type amino acid transporter 1; Monocyte amino acid permease 2; LPI; Solute carrier family 7 member 7; LAT3; MOP-2; Y+L amino acid transporter 1; OTTHUMP00000027913; OTTHUMP00000164491; OTTHUMP00000164492; OTTHUMP00000164493; OTTHUMP00000164494
Product Background
Antigen Description
The protein encoded by this gene is the light subunit of a cationic amino acid transporter. This sodium-independent transporter is formed when the light subunit encoded by this gene dimerizes with the heavy subunit transporter protein SLC3A2. This transporter is found in epithelial cell membranes where it transfers cationic and large neutral amino acids from the cell to the extracellular space. Defects in this gene are a cause of lysinuric protein intolerance (LPI). Alternative splicing results in multiple transcript variants.Mouse monoclonal antibody raised against a partial recombinant SLC7A7.
Pathway
Amino acid transport across the plasma membrane, organism-specific biosystem; Basigin interactions, organism-specific biosystem; Cell surface interactions at the vascular wall, organism-specific biosystem; Hemostasis, organism-specific biosystem; Metabolism of amino acids and derivatives, organism-specific biosystem; Protein digestion and absorption, organism-specific biosystem
Citations
Publication ()
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COA
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