HTLV Glycoprotein 46 Mosaic protein (DAG1571)

HTLV Glycoprotein 46 Mosaic protein, recombinant protein from E. coli Datasheet

Online Inquiry Add to basket

Product Overview
Recombinant HTLV gp46 protein containing the gp46 immunodominant regions, 162-214 amino acids and 242-257 amino acids was expressed in E. coli and purified by proprietary chromatographic technique.
> 95% pure as determined by 10% SDS-PAGE (coomassie staining) and RP-HPLC.
10mM NaPO4 pH 6.0, 0.1% SDS, 1mM DTT, 1mM EDTA.
2-8°C short term, -20°C long term
Human T-lymphotropic virus (HTLV) is a human, single-stranded RNA retrovirus that causes T-cell leukemia and T-cell lymphoma. The virus activates a subset of T-helper cellscalled Th1cells. The result is a proliferation of Th1 cells and overproduction of Th1 related cytokines (mainly IFN-gamma and TNF-alpha). Feedback mechanisms of these cytokines cause a suppression of the Th2 lymphocytes and a reduction of Th2 cytokine production (mainly IL-4, IL-5, IL-10 and IL-13). The end result is a reduction in the ability of the infected host to mount an adequate immune response to invading organisms that require a predominantly Th2 dependant response (these include parasitic infections and production of mucosal and humoral antibodies).
HTLV-I gp46; Glycoprotein 46; SU; Surface protein; HTLV-I gp46 antigen; Deltaretrovirus; Retroviridae; Human T-lymphotropic virus Type I; T-lymphotropic virus Type I Gp46; HTLV-1; Adult T-cell lymphoma virus type 1; Human T-lymphotropic Virus Type I Gp46


Have you cited DAG1571 in a publication? Let us know and earn a reward for your research.

Customer Reviews

Write a review, share your experiences with others and get rewarded !

Online Inquiry

Phone *
E-mail Address *
Service & Products Interested *
Project Description
Verification Code * Please input "diagnostics" as verification code.

Online Inquiry

Order Info: HTLV Glycoprotein 46 Mosaic protein

Online Inquiry
  Interested in larger quantities ? request a quote!
  Protocol may be improved. Please feel free to contact us to obtain the latest version.!
  15% off your first purchase

Ordering Information

Payment methods we support:
Invoice / Purchase Order
Credit card

OUR PROMISE TO YOU Guaranteed product quality expert customer support

Inquiry Basket