Product Overview
Recombinant Hepatitis B 'e' Antigen immunodominant region,contains10 precore residues at its N-terminus and 1-149 residues from the end of precore to its C-terminus, and 6-His fusion partner was expressed in Ecoli, and puried in vitro using conventional chromatography techniques.
Purity
>95% pure (12% PAGE (Coomassie staining)). Proprietary chromatographic technique
Buffer
20mM Tris-Hcl, 0.5M NaCl
Preservative
0.8M imidazole
Storage
2-8°C short term, -20°C long term
Antigen Description
Hepatitis B e-antigen (HBeAg) is a viral protein associated with HBV infections. Unlike the surface antigen, the e-antigen is found in the blood only when there are viruses also present. When the virus goes into hiding, the e-antigen will no longer be present in the blood. HBeAg is often used as a marker of ability to spread the virus to other people (infectivity). Measurement of e-antigen may also be used to monitor the effectiveness of HBV treatment; successful treatment will usually eliminate HBeAg from the blood and lead to development of antibodies against e-antigen (anti-HBe). There are some types (strains) of HBV that do not make e-antigen; these are especially common in the Middle East and Asia. In areas where these strains of HBV are common, testing for HBeAg is not very useful.
Keywords
hepatitis B e antigen; HBeAg; HBV; Hepatitis B Virus; Hepatitis B 'E' Antigen
Citations
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