Product Overview
HCV NS4 antigen (recombinant) NS4a+b a.a 1658 to a.a 1863 of HCV polyprotein. 19kDa with Betagalactosidase (114kDa) fused at N-terminus. Immunoreactive with HCV positive serum.
Tag/Conjugate
Beta-galactosidase
Alternative Names
HCV NS4; HCV; HCV Nonstructural Protein 4A, B; HCV NS4a; HCV NS4b
Purity
> 95% Pure (SDS-PAGE)
Buffer
20 mM Tris-HCl, pH 8.0, 2 mM beta-Mercaptoethanol.
Storage
Store at 2-8°C. DO NOT FREEZE.
Introduction
Hepatitis C Virus is a positive, single stranded RNA virus in the Flaviviridae family. The genome is approximately 10, 000 nucleotides and encodes a single polyprotein of about 3, 000 amino acids. The polyprotein is processed by host cell and viral proteases into three major structural proteins and several non structural proteins necessary for viral replication. Several different genotypes of HCV with slightly different genomic sequences have since been identified that correlate with differences in response to treatment with interferon alpha.
Keywords
HCV NS4; HCV; HCV Nonstructural Protein 4A, B; HCV NS4a; HCV NS4b
Citations
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