Recombinant Epstein Barr Virus Early Antigen
Immunoreactive with sera of EBV-infected individuals.
> 95% pure by 10% PAGE (Coomassie staining)
50 mM Tris-HCl, 10mM glutation, 60 mM NaCl, 0.5% sarcosyl, 50% glycerol
2-8°C short term, -20°C long term
The Epstein–Barrvirus (EBV), also called human herpesvirus5(HHV-4), is a virus of theherpes family, which includes herpes simplex virus 1 and 2, and is one of themost common viruses in humans. It is best known as the cause of infectiousmononucleosis. It is also associated with particular forms of cancer, particularlyHodgkin"s lymphoma, Burkitt"s lymphoma, nasopharyngeal carcinoma, and centralnervous system lymphomas associated with HIV. Finally, there is evidence thatinfection with the virus is associated with a higher risk of certainautoimmune diseases, especially dermatomyositis, systemic lupuserythematosus, rheumatoid arthritis and multiplesclerosis.
Epstein-Barr virus (EBV) early antigens are a group of non-structural proteins, the synthesis of which do not require viral DNA replication. At least two forms of early antigen have been identified on the basis of their distribution in the cell, namely di
BMRF1; Early antigen; EBV EA; EBV early antigen; Epstein Barr virus EA; Epstein Barr virus early antigen; Epstein Barr virus early antigen; HHV4 EA; HHV4 early antigen; HHV4 early antigen; Human herpesvirus 4 EA; Humanherpesvirus 4 early antigen diffuse E