EBV Early Antigen (DAG3130)

EBV Early Antigen, recombinant protein from E. coli

Product Overview
Recombinant Epstein Barr Virus Early Antigen
Specificity
Immunoreactive with sera of EBV-infected individuals.
Nature
Recombinant
Tag/Conjugate
Unconjugated
Procedure
None
Purity
> 95% pure by 10% PAGE (Coomassie staining)
Format
Liquid
Buffer
50 mM Tris-HCl, 10mM glutation, 60 mM NaCl, 0.5% sarcosyl, 50% glycerol
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
The Epstein–Barrvirus (EBV), also called human herpesvirus5(HHV-4), is a virus of theherpes family, which includes herpes simplex virus 1 and 2, and is one of themost common viruses in humans. It is best known as the cause of infectiousmononucleosis. It is also associated with particular forms of cancer, particularlyHodgkin"s lymphoma, Burkitt"s lymphoma, nasopharyngeal carcinoma, and centralnervous system lymphomas associated with HIV. Finally, there is evidence thatinfection with the virus is associated with a higher risk of certainautoimmune diseases, especially dermatomyositis, systemic lupuserythematosus, rheumatoid arthritis and multiplesclerosis.
Antigen Description
Epstein-Barr virus (EBV) early antigens are a group of non-structural proteins, the synthesis of which do not require viral DNA replication. At least two forms of early antigen have been identified on the basis of their distribution in the cell, namely di
Keywords
BMRF1; Early antigen; EBV EA; EBV early antigen; Epstein Barr virus EA; Epstein Barr virus early antigen; Epstein Barr virus early antigen; HHV4 EA; HHV4 early antigen; HHV4 early antigen; Human herpesvirus 4 EA; Humanherpesvirus 4 early antigen diffuse E

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References


YAO, QY; ROWE, M; et al. SALIVARY AND SERUM IGA ANTIBODIES TO THE EPSTEIN-BARR-VIRUS GLYCOPROTEIN GP340 - INCIDENCE AND POTENTIAL FOR VIRUS NEUTRALIZATION. INTERNATIONAL JOURNAL OF CANCER 48:45-50(1991).
Stevens, SJC; Zwaan, CM; et al. Epstein-Barr virus (EBV) serology for predicting distant metastases in a white juvenile patient with nasopharyngeal carcinoma and no clinical response to EBV lytic induction therapy. HEAD AND NECK-JOURNAL FOR THE SCIENCES AND SPECIALTIES OF THE HEAD AND NECK 28:1040-1045(2006).

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