Human DROSHA blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-RNASEN/Drosha antibody

Target

RNASEN / Drosha

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

Members of the ribonuclease III superfamily of double-stranded (ds) RNA-specific endoribonucleases participate in diverse RNA maturation and decay pathways in eukaryotic and prokaryotic cells (Fortin et al., 2002 [PubMed 12191433]). The RNase III Drosha is the core nuclease that executes the initiation step of microRNA (miRNA) processing in the nucleus (Lee et al., 2003 [PubMed 14508493]).

Function

double-stranded RNA binding; endonuclease activity; hydrolase activity; metal ion binding; protein binding; ribonuclease III activity;

Synonyms

DROSHA; drosha, ribonuclease type III; ribonuclease type III, nuclear , RNASEN; ribonuclease 3; drosha; double stranded RNA specific endoribonuclease; ribonuclease type III; Etohi2; HSA242976; RN3; RNASE3L; p241; RNase III; protein Drosha; nuclear RNase III Drosha; putative ribonuclease III; ribonuclease III, nuclear; ribonuclease type III, nuclear; drosha, double-stranded RNA-specific endoribonuclease; putative protein p241 which interacts with transcription factor Sp1; ETOHI2; RNASEN; RANSE3L;