Product Overview
Blocking/Immunizing peptide for anti-Pallidin antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Function
actin binding; muscle alpha-actinin binding; protein binding;
Synonyms
PALLD; palladin, cytoskeletal associated protein; MYN; PNCA1; CGI151; SIH002; CGI-151; palladin; myoneurin; sarcoma antigen NY-SAR-77;
Citations
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Shiffman, D; Ellis, SG; et al. Identification of four gene variants associated with myocardial infarction. AMERICAN JOURNAL OF HUMAN GENETICS 77:596-605(2005).
Beck, MR; Otey, CA; et al. Structural Characterization of the Interactions between Palladin and alpha-Actinin. JOURNAL OF MOLECULAR BIOLOGY 413:712-725(2011).