Product Overview
Blocking/Immunizing peptide for anti-Palladin antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes a cytoskeletal protein that is required for organizing the actin cytoskeleton. The protein is a component of actin-containing microfilaments, and it is involved in the control of cell shape, adhesion, and contraction. Polymorphisms in this gene are associated with a susceptibility to pancreatic cancer type 1, and also with a risk for myocardial infarction. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2009]
Function
actin binding; muscle alpha-actinin binding; protein binding;
Synonyms
PALLD; palladin, cytoskeletal associated protein; MYN; PNCA1; CGI151; SIH002; CGI-151; palladin; myoneurin; sarcoma antigen NY-SAR-77;
Citations
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Boukhelifa, M; Hwang, SJ; et al. A critical role for palladin in astrocyte morphology and response to injury. MOLECULAR AND CELLULAR NEUROSCIENCE 23:661-668(2003).
Moza, M; Mologni, L; et al. Targeted deletion of the muscular dystrophy gene myotilin does not perturb muscle structure or function in mice. MOLECULAR AND CELLULAR BIOLOGY 27:244-252(2007).