Product Overview
Blocking/Immunizing peptide for anti-PSMA4 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]
Function
peptidase activity; protein binding; threonine-type endopeptidase activity;
Synonyms
PSMA4; proteasome (prosome, macropain) subunit, alpha type, 4; proteasome subunit alpha type-4; HC9; HsT17706; macropain subunit C9; proteasome subunit L; proteasome subunit HC9; proteasome component C9; multicatalytic endopeptidase complex subunit C9; PSC9; MGC12467; MGC24813; MGC111191;
Citations
Publication ()
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