The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]
Function
DNA binding; death receptor binding; metal ion binding; zinc ion binding;
Synonyms
PRDM4; PR domain containing 4; PR domain zinc finger protein 4; PFM1; PR domain-containing protein 4; PR-domain zinc-finger protein PFM1; MGC45046;
Citations
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