Recombinant human PRDM4 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 451-801 aa of BC035581
Conjugate
Unconjugated
Applications
Application Notes
WB: 1:500-1:1000
General Notes
This product (Catalog No. DPABH-23010) is a rabbit-derived polyclonal antibody raised against human PRDM4, targeting the amino acid region 451–801 of the protein. This antibody exhibits cross-reactivity with Human PRDM4 from mouse and rat. It has been affinity purified by Protein A. The PRDM family members are characterized by the presence of a PR (positive regulatory) domain and multiple zinc finger (ZnFg) domains. The PR domain defines a family of transcription factors involved in cell differentiation and tumorigenesis. PRDM proteins are either epigenetic modifiers in their own right or else they recruit third party chromatin modifiers - e.g. histone deacetylases (HDACs), histone lysine MTases or histone arginine MTases - to regulate cell type-specific gene expression in various tissues (PRDM4 as an HDAC-associated transcriptional repressor that modulates cell cycle progression. DPABH-23010 is suitable for use in Western blot (WB) (1:500–1:1,000) application. DPABH-23010 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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