PRDM4 (NP_036538, 476 a.a. ~ 575 a.a) partial recombinant protein with GST tag. The sequence is IITTDENECNWMMFVRKARNREEQNLVAYPHDGKIFFCTSQDIPPENELLFYYSRDYAQQ IGVPEHPDVHLCNCGKECNSYTEFKAHLTSHIHNHLPTQG
Conjugate
Unconjugated
Target
Alternative Names
PRDM4; PR domain containing 4; PFM1; PR domain zinc finger protein 4; PR domain-containing protein 4; PR-domain zinc-finger protein PFM1;
The protein encoded by this gene is a transcription factor of the PR-domain protein family. It contains a PR-domain and multiple zinc finger motifs. Transcription factors of the PR-domain family are known to be involved in cell differentiation and tumorigenesis. An elevated expression level of this gene has been observed in PC12 cells treated with nerve growth factor, beta polypeptide (NGF). This gene is located in a chromosomal region that is thought to contain tumor suppressor genes.
Pathway
Neurotrophin signaling pathway; Signal Transduction; p75 NTR receptor-mediated signalling; p75NTR negatively regulates cell cycle via SC1
Citations
Publication ()
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COA
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