Product Overview
Blocking/Immunizing peptide for anti-PPP2R3A (aa721-31) antibody
Target
PPP2R3A (aa721-31)
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes one of the regulatory subunits of the protein phosphatase 2. Protein phosphatase 2 (formerly named type 2A) is one of the four major Ser/Thr phosphatases and is implicated in the negative control of cell growth and division. Protein phosphatase 2 holoenzymes are heterotrimeric proteins composed of a structural subunit A, a catalytic subunit C, and a regulatory subunit B. The regulatory subunit is encoded by a diverse set of genes that have been grouped into the B/PR55, B'/PR61, and B''/PR72 families. These different regulatory subunits confer distinct enzymatic specificities and intracellular localizations to the holozenzyme. The product of this gene belongs to the B'' family. The B'' family has been further divided into subfamilies. The product of this gene belongs to the alpha subfamily of regulatory subunit B''. Alternative splicing results in multiple transcript variants encoding different isoforms.[provided by RefSeq, Jun 2010]
Function
calcium ion binding; protein binding; protein phosphatase type 2A regulator activity;
Synonyms
PPP2R3A; protein phosphatase 2, regulatory subunit B, alpha; PPP2R3, protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 72), alpha isoform and (PR 130), beta isoform , protein phosphatase 2 (formerly 2A), regulatory subunit B, alpha; serine/threonine-protein phosphatase 2A regulatory subunit B subunit alpha; PP2A, subunit B, R3 isoform; PP2A subunit B isoforms B72/B130; serine/threonine-protein phosphatase 2A 72/130 kDa regulatory subunit B; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR 72), alpha isoform and (PR 130), beta isoform; PR72; PR130; PPP2R3;
Citations
Publication ()
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