Anti-PPP2R2A monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human PPP2R2A is used for rabbit immunization.

Conjugate

Alternative Names

PPP2R2A; protein phosphatase 2, regulatory subunit B, alpha; B55A; PR52A; PR55A; B55ALPHA; serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform; protein phosphatase 2 (formerly 2A), regulatory subunit B (PR52), alpha isoform;

Entrez Gene ID

UniProt ID

Antigen Description

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes an alpha isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants have been described.

Pathway

Adrenergic signaling in cardiomyocytes; Canonical Wnt signaling pathway; Cell Cycle; Cell Cycle, Mitotic; Chagas disease (American trypanosomiasis); Cyclin A/B1 associated events during G2/M transition; Cyclin D associated events in G1; Dopaminergic synapse; ErbB1 downstream signaling; G1 Phase; G2/M Transition;