This product (Catalog No. DPABH-22606) is a rabbit-derived polyclonal antibody raised against human PPP2R2A, targeting the amino acid region 99–447 of the protein. This antibody exhibits cross-reactivity with Human PPP2R2A from mouse and rat. It has been affinity purified by Protein A. The serine/threonine protein phosphatase 2A (PP2A) is a master regulator of the complex cellular signaling that occurs during all stages of mammalian development. PPP2R2A, also known as B55A or PR55A, is a regulatory subunit of PP2A expressed in an Akt-dependent manner in epidermis during barrier formation. PPP2R2A participates in the negative control of cell growth and division. PPP2R2A has been proved to be a tumor suppressor that can inhibit the proliferation of a variety of cancer cells, such as prostate cancer cells(PMID: 21872824). DPABH-22606 is suitable for use in Western blot (WB) (1:500–1:1,000), IHC (1:200–1:800), IF/ICC (1:200–1:800) applications. DPABH-22606 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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