Human PIAS2 blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-PIAS2 antibody

Target

PIAS2

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene encodes a member of the protein inhibitor of activated STAT (PIAS) family. PIAS proteins function as SUMO E3 ligases and play important roles in many cellular processes by mediating the sumoylation of target proteins. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. Isoforms of the encoded protein enhance the sumoylation of specific target proteins including the p53 tumor suppressor protein, c-Jun, and the androgen receptor. A pseudogene of this gene is located on the short arm of chromosome 4. The symbol MIZ1 has also been associated with ZBTB17 which is a different gene located on chromosome 1. [provided by RefSeq, Aug 2011]

Function

DNA binding; SUMO ligase activity; androgen receptor binding; ligase activity; metal ion binding; protein binding; transcription coactivator activity; ubiquitin protein ligase binding; zinc ion binding;

Synonyms

PIAS2; protein inhibitor of activated STAT, 2; E3 SUMO-protein ligase PIAS2; miz; PIASX ALPHA; PIASX BETA; zinc finger; MIZ type containing 4; ZMIZ4; DAB2-interacting protein; zinc finger, MIZ-type containing 4; msx-interacting zinc finger protein; protein inhibitor of activated STAT X; androgen receptor-interacting protein 3; DIP; MIZ; MIZ1; SIZ2; ARIP3; PIASX; PIASX-BETA; PIASX-ALPHA; MGC102682;