Human PCNA blocking peptide (CDBP2221)

Synthetic Human PCNA blocking peptide for BL Datasheet

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Product Overview
PCNA ( C - term ) peptide ( human )
Target
PCNA
Nature
Synthetic
Species Reactivity
Human
Tag/Conjugate
Unconjugated
Concentration
0.2 mg/ml
Size
500 μl
Buffer
Preservative: 0.1% Sodium Azide; Constituents: PBS, 100μg/ml BSA
Storage
Store this product at 4 °C, do not freeze. The product is stable for one year from the date of shipment.
UniProt ID
Antigen Description
The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]
Function
DNA binding; DNA polymerase processivity factor activity; MutLalpha complex binding; dinucleotide insertion or deletion binding; identical protein binding; protein binding; purine-specific mismatch base pair DNA N-glycosylase activity; receptor tyrosine k
Synonyms
PCNA; proliferating cell nuclear antigen; cyclin; DNA polymerase delta auxiliary protein; MGC8367;

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