Human PCNA blocking peptide

Product Overview

PCNA ( C - term ) peptide ( human )

Target

PCNA

Nature

Synthetic

Tag/Conjugate

Unconjugated

Concentration

0.2 mg/ml

Buffer

Preservative: 0.1% Sodium Azide; Constituents: PBS, 100μg/ml BSA

Preservative

0.1% Sodium Azide

Storage

Store this product at 4 °C, do not freeze. The product is stable for one year from the date of shipment.

Entrez Gene ID

Antigen Description

The protein encoded by this gene is found in the nucleus and is a cofactor of DNA polymerase delta. The encoded protein acts as a homotrimer and helps increase the processivity of leading strand synthesis during DNA replication. In response to DNA damage, this protein is ubiquitinated and is involved in the RAD6-dependent DNA repair pathway. Two transcript variants encoding the same protein have been found for this gene. Pseudogenes of this gene have been described on chromosome 4 and on the X chromosome. [provided by RefSeq, Jul 2008]

Function

DNA binding; DNA polymerase processivity factor activity; MutLalpha complex binding; dinucleotide insertion or deletion binding; identical protein binding; protein binding; purine-specific mismatch base pair DNA N-glycosylase activity; receptor tyrosine k

Synonyms

PCNA; proliferating cell nuclear antigen; cyclin; DNA polymerase delta auxiliary protein; MGC8367;