Specifications
Species Reactivity
Mouse; Rat; Chicken; Human; Fruit fly; Zebrafish
Immunogen
Protein A-rat PCNA (proliferating cell nuclear antigen) fusion obtained from pC2T.
Applications
Application Notes
ICC/IF: 5 μg/ml.
Target
Alternative Names
PCNA; proliferating cell nuclear antigen; cyclin; PCNAR; Pcna/cyclin;
Product Background
Antigen Description
This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerases processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3-5 exonuclease and 3-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.
Pathway
BRCA1-associated genome surveillance complex (BASC), organism-specific biosystem; Base Excision Repair, organism-specific biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; Cell cycle, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-9564 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
