Product Overview
Blocking/Immunizing peptide for anti-PARP2 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes poly(ADP-ribosyl)transferase-like 2 protein, which contains a catalytic domain and is capable of catalyzing a poly(ADP-ribosyl)ation reaction. This protein has a catalytic domain which is homologous to that of poly (ADP-ribosyl) transferase, but lacks an N-terminal DNA binding domain which activates the C-terminal catalytic domain of poly (ADP-ribosyl) transferase. The basic residues within the N-terminal region of this protein may bear potential DNA-binding properties, and may be involved in the nuclear and/or nucleolar targeting of the protein. Two alternatively spliced transcript variants encoding distinct isoforms have been found. [provided by RefSeq, Jul 2008]
Function
DNA binding; NAD+ ADP-ribosyltransferase activity; transferase activity, transferring glycosyl groups;
Synonyms
PARP2; poly (ADP-ribose) polymerase 2; ADP ribosyltransferase (NAD+; poly(ADP ribose) polymerase) like 2 , ADPRTL2, poly (ADP ribose) polymerase family, member 2; poly [ADP-ribose] polymerase 2; ADPRT-2; hPARP-2; poly(ADP-ribose) synthetase; poly[ADP-ribose] synthase 2; poly[ADP-ribose] synthetase 2; NAD(+) ADP-ribosyltransferase 2; poly (ADP-ribosyl) transferase-like 2; poly (ADP-ribose) polymerase family, member 2; ADP-ribosyltransferase (NAD+; poly(ADP-ribose) polymerase)-like 2; ADPRT2; PARP-2; ADPRTL2; ADPRTL3; pADPRT-2;
Citations
Publication ()
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