Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Recombinant protein within human parp2.
Applications
Application Notes
WB: 1/1000 - 1/5000; ICC: 1/200;
Target
Alternative Names
PARP2; poly (ADP-ribose) polymerase 2; ADP ribosyltransferase (NAD+; poly(ADP ribose) polymerase) like 2 , ADPRTL2, poly (ADP ribose) polymerase family, member 2; poly [ADP-ribose] polymerase 2; ADPRT-2; hPARP-2; poly(ADP-ribose) synthetase; poly[ADP-rib
Product Background
Antigen Description
Involved in the base excision repair (BER) pathway, by catalyzing the poly(ADP-ribosyl)ation of a limited number of acceptor proteins involved in chromatin architecture and in DNA metabolism. This modification follows DNA damages and appears as an obligatory step in a detection/signaling pathway leading to the reparation of DNA strand breaks.
Pathway
BER complex, organism-specific biosystem; BER complex, conserved biosystem; Base excision repair, organism-specific biosystem; Base excision repair, conserved biosystem; Regulation of Telomerase, organism-specific biosystem;
Citations
Publication ()
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COA
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