Product Overview
Blocking/Immunizing peptide for anti-PAR6alpha/PARD6A antibody
Target
PAR6alpha / PARD6A
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008]
Function
GTP-dependent protein binding; Rho GTPase binding; protein binding; protein kinase C binding; transcription factor binding;
Synonyms
PARD6A; par-6 partitioning defective 6 homolog alpha (C. elegans); par 6 (partitioning defective 6, C.elegans) homolog alpha; partitioning defective 6 homolog alpha; PAR 6; PAR 6A; PAR6alpha; TAX40; TIP 40; PAR-6 alpha; Tax-interacting protein 40; tax interaction protein 40; partitioning-defective protein 6; partitioning defective-6 homolog alpha; PAR6; PAR6C; PAR-6A; TIP-40;
Citations
Publication ()
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