Specifications
Species Reactivity
Mouse; Rat; Human
Immunogen
Synthetic peptide (the amino acid sequence is considered to be commercially sensitive) within Human PAR6 aa 1-100 (Cysteine residue). The exact sequence is proprietary.Database link: Q9NPB6
Applications
Application Notes
IP: 1/10 - 1/100; WB: 1/1000 - 1/10000.
Target
Alternative Names
PARD6A; par-6 partitioning defective 6 homolog alpha (C. elegans); par 6 (partitioning defective 6, C.elegans) homolog alpha; partitioning defective 6 homolog alpha; PAR 6; PAR 6A; PAR6alpha; TAX40; TIP 40; PAR-6 alpha; Tax-interacting protein 40; tax int
Product Background
Antigen Description
Adapter protein involved in asymmetrical cell division and cell polarization processes. Probably involved in the formation of epithelial tight junctions. Association with PARD3 may prevent the interaction of PARD3 with F11R/JAM1, thereby preventing tight junction assembly. The PARD6-PARD3 complex links GTP-bound Rho small GTPases to atypical protein kinase C proteins.
Pathway
CDC42 signaling events, organism-specific biosystem; Cell junction organization, organism-specific biosystem; Cell-Cell communication, organism-specific biosystem; Cell-cell junction organization, organism-specific biosystem; Endocytosis, organism-specific biosystem; Endocytosis, conserved biosystem; Insulin Pathway, organism-specific biosystem;
Citations
Publication ()
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COA
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