Fusion protein corresponding to residues near the C terminal of human par-6 family cell polarity regulator alpha
Conjugate
Unconjugated
Applications
Application Notes
IHC: 1:50-1:200
General Notes
This product (Catalog No. DPABH-27489) is a rabbit-derived IgG polyclonal antibody raised against human PARD6A. It has been affinity purified by protein A. This gene is a member of the PAR6 family and encodes a protein with a PSD95/Discs-large/ZO1 (PDZ) domain and a semi-Cdc42/Rac interactive binding (CRIB) domain. This cell membrane protein is involved in asymmetrical cell division and cell polarization processes as a member of a multi-protein complex. The protein also has a role in the epithelial-to-mesenchymal transition (EMT) that characterizes the invasive phenotype associated with metastatic carcinomas. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. DPABH-27489 is suitable for use in IHC (1:50–1:200) application. DPABH-27489 is supplied as a liquid formulation in pH7.4 PBS, 0.05% sodium azide, 40% Glycerol. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.
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