Specificity
Most abundant in the brain, low expression in the lung, liver, thymus, spleen, pancreas and placenta.
Tag/Conjugate
Unconjugated
SequenceSimilarities
Belongs to the G-protein coupled receptor 2 family.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Antigen Description
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
Function
ADP-ribosylation factor binding; adenylate cyclase binding; neuropeptide binding; protein binding; receptor activity; vasoactive intestinal polypeptide receptor activity;
Synonyms
ADCYAP1R1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC1; PAC1R; PACAPR; PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; PACAP receptor 1; PACAP type I receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop;
Citations
Publication ()
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