Synthetic peptide corresponding to a region within C terminal amino acids 325-374 (GIIIILVQKL QSPDMGGNES SIYFSCVQKC YCKPQRAQQH SCKMSELSTI) of Rat PACAP receptor, isoform 2 (NP_598195).
Conjugate
Unconjugated
Target
Alternative Names
ADCYAP1R1; adenylate cyclase activating polypeptide 1 receptor 1; PAC1-R; PACAPR1; PACAP-R1; PACAPR1A; PACAP-R1A; pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R-1; PACAP-R-1A; PACAP type I receptor; PACAP type IA receptor; ade
This is a receptor for PACAP-27 and PACAP-38. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. May regulate the release of adrenocorticotropin, luteinizing hormone, growth hormone, prolactin, epinephrine, and catecholamine. May play a role in spermatogenesis and sperm motility. Causes smooth muscle relaxation and secretion in the gastrointestinal tract.
Pathway
Activation of TRKA receptors; Circadian entrainment; G alpha (s) signalling events; GPCR ligand binding.
Citations
Publication ()
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