Product Overview
Blocking/Immunizing peptide for anti-PACAP antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
This gene encodes type I adenylate cyclase activating polypeptide receptor, which is a membrane-associated protein and shares significant homology with members of the glucagon/secretin receptor family. This receptor mediates diverse biological actions of adenylate cyclase activating polypeptide 1 and is positively coupled to adenylate cyclase. Multiple alternatively spliced transcript variants encoding distinct isoforms have been identified. [provided by RefSeq, Dec 2010]
Function
ADP-ribosylation factor binding; adenylate cyclase binding; neuropeptide binding; protein binding; receptor activity; vasoactive intestinal polypeptide receptor activity;
Synonyms
ADCYAP1R1; adenylate cyclase activating polypeptide 1 (pituitary) receptor type I; PAC1; PAC1R; PACAPR; PACAPRI; pituitary adenylate cyclase-activating polypeptide type I receptor; PACAP-R1; PACAP receptor 1; PACAP type I receptor; pituitary adenylate cyclase activating polypeptide 1 receptor type I Hiphop;
Citations
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Le, SV; Yamaguchi, DJ; et al. PAC1 and PACAP expression, signaling, and effect on the growth of HCT8, human colonic tumor cells. REGULATORY PEPTIDES 109:115-125(2002).
Miampamba, M; Germano, PM; et al. Expression of pituitary adenylate cyclase-activating polypeptide and PACAP type 1 receptor in the rat gastric and colonic myenteric neurons. REGULATORY PEPTIDES 105:145-154(2002).