Product Overview
Blocking/Immunizing peptide for anti-ORC6L antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
The origin recognition complex (ORC) is a highly conserved six subunit protein complex essential for the initiation of the DNA replication in eukaryotic cells. Studies in yeast demonstrated that ORC binds specifically to origins of replication and serves as a platform for the assembly of additional initiation factors such as Cdc6 and Mcm proteins. The protein encoded by this gene is a subunit of the ORC complex. Gene silencing studies with small interfering RNA demonstrated that this protein plays an essential role in coordinating chromosome replication and segregation with cytokinesis. [provided by RefSeq, Oct 2010]
Function
DNA binding; protein binding;
Synonyms
ORC6; origin recognition complex, subunit 6; ORC6L; origin recognition complex subunit 6;
Citations
Have you cited CDBP2130 in a publication?
Let us know and earn a reward for your research.
| Product Name |
Cat. No. |
Applications |
Host Species |
Datasheet |
Price |
Add to Basket |
| Product Name |
Cat. No. |
Applications |
Host Species |
Datasheet |
Price |
Add to Basket |
Murai, S; Schultz, R; et al. Orc6l mRNA: a maternal mRNA required for DNA replication in zygotes. BIOLOGY OF REPRODUCTION :71-71(2008).
Killian, A; Sarafan-Vasseur, N; et al. Contribution of the BOP1 gene, located on 8q24, to colorectal tumorigenesis. GENES CHROMOSOMES & CANCER 45:874-881(2006).