Tag/Conjugate
Unconjugated
Antigen Description
This gene encodes a coiled-coil protein that plays a role in multiple processes including cytoskeletal organization, cell signaling and neuron migration, outgrowth and maintenance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome X. [provided by RefSeq, Mar 2012]
Function
alpha-tubulin binding; beta-tubulin binding; microtubule binding; oligopeptidase activity; protein binding
Synonyms
NDEL1; nudE neurodevelopment protein 1-like 1; EOPA; NDE2; NUDEL; MITAP1; NDE1L1; nuclear distribution protein nudE-like 1; protein Nudel; endooligopeptidase A; mitosin-associated protein 1; mitosin-associated protein MITAP1; nudE nuclear distribution E homolog-like 1; nudE nuclear distribution gene E homolog-like 1
Citations
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Leliveld, SR; Hendriks, P; et al. Oligomer Assembly of the C-Terminal DISC1 Domain (640-854) Is Controlled by Self-Association Motifs and Disease-Associated Polymorphism S704C. BIOCHEMISTRY 48:7746-7755(2009).
Yamada, M; Toba, S; et al. LIS1 and NDEL1 coordinate the plus-end-directed transport of cytoplasmic dynein. EMBO JOURNAL 27:2471-2483(2008).