Anti-NDEL1 monoclonal antibody Made to order

Antibody Isotype

IgG

Species Reactivity

Human

Immunogen

A synthetic peptide of human NDEL1 is used for rabbit immunization.

Conjugate

Alternative Names

NDEL1; nudE nuclear distribution E homolog (A. nidulans)-like 1; nudE nuclear distribution gene E homolog (A. nidulans) like 1; nuclear distribution protein nudE-like 1; MITAP1; NUDEL; protein Nudel; endooligopeptidase A; mitosin-associated protein 1; mit

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a thiol-activated peptidase that is phosphorylated in M phase of the cell cycle. Phosphorylation regulates the cell cycle-dependent distribution of this protein, with a fraction of the protein bound strongly to centrosomes in interphase and localized to mitotic spindles in early M phase. Overall, this protein plays a role in nervous system development. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Pathway

Aurora A signaling, organism-specific biosystem; Cell Cycle, organism-specific biosystem; Cell Cycle, Mitotic, organism-specific biosystem; DNA Replication, organism-specific biosystem; Lissencephaly gene (LIS1) in neuronal migration and development, organism-specific biosystem; M Phase, organism-specific biosystem; Mitotic M-M/G1 phases, organism-specific biosystem;