Human NTx Serum ELISA Kit

Sample

serum

Species Reactivity

Human

Detection Method

Competitive ELISA

Intended Use

A Serum NTx level is used to aid in predicting skeletal response (bone mineral density) to antiresorptive therapy and in monitoring bone resorption changes following initiation of antiresorptive therapy. Prior to initiating antiresorptive therapy, a serum NTx level is used to determine the probability for a decrease in bone mineral density (BMD) after one year in postmenopausal women treated with hormonal antiresorptive therapy relative to those treated with calcium supplementation.
The measurement range of NTx Serum is 3.2 to 40.0 nM Bone Collagen Equivalents (BCE).

Storage

Reagents must be stored at 2 - 8°C when not in use. Reagents must be brought to room temperature before use. Do not expose reagents to temperatures greater than 25°C. Diluted wash solution may be stored at room temperature for up to one month.

Precision

Total assay precisionwas evaluated by testing the Level I Serum Control (9.4 nM BCE) and the Level II Serum Control (30.0 nM BCE) at four clinical laboratories.
The estimate for the total precision% CV for the Level I Serum Control was 13.99%, and for the Level II Serum Control was 11.92%.