Mycoplasma Identification and Susceptibility Test Kit

Name: Mycoplasma Identification and Susceptibility Test Kit
SKU: MIESTK1
Rating: 5 (1 reviews)

Regulatory status: For research use only, not for use in diagnostic procedures.

COA

SDS

Datasheet

Summary

Sample

Vaginal swab, urethral swab, rectal swab, seminal fluid

Intended Use

The kit is used for culture isolation, identification, enumeration of Ureaplasma urealyticum (UU) and Mycoplasma hominis (MH) from urogenital specimens and susceptibility determination of 12 commonly used antibiotics.

Storage

The package should be stored 2-8 °C until the expiration date indicated on the label.

General Description

Mycoplasma is the cause of Nongonococcal Urethritis (NGU), cervical, pelvic inflammatory disease, orchitis, epididymitis, and other disorders of the main pathogens. It may cause infertility to men and women. These pathogens can attack and destroy genitourinary epithelial cells, causing infectivity of AIDS and other sexually transmitted disease. Clinical sexually transmitted diseases can be caused by Mycoplasma, including the main UU and MH, which are the most commonly found. Its incidence has been on the rise along with antibiotic resistance that has become a serious harm to human health. Timely and accurate diagnosis is the key to treatment and prevention of the Mycoplasma spread.
Mycoplasma lacks a cell wall and hence a natural resistance to β-lactams, it only grows in acellular cultures in the presence of various growth factors and at a constant temperature of 35 to 37 °C. Both UU and MH are commensal, infection can only be diagnosed through the determination of the pathological threshold, followed by precise enumeration.

Citations

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Documents

pdf COA

pdf SDS

pdf Datasheet

QA & Reviews

Customer Reviews

References

The pathogenMycoplasma disparShows High Minimum Inhibitory Concentrations for Antimicrobials Commonly Used for Bovine Respiratory Disease

ANTIBIOTICS-BASEL

Authors: Bottinelli, Marco; Merenda, Marianna; Gastaldelli, Michele; Picchi, Micaela; Stefani, Elisabetta; Nicholas, Robin A. J.; Catania, Salvatore

Abstract

Mycoplasma disparis an overlooked pathogen often involved in bovine respiratory disease (BRD), which affects cattle around the world. BRD results in lost production and high treatment and prevention costs. Additionally, chronic therapies with multiple antimicrobials may lead to antimicrobial resistance. Data on antimicrobial susceptibility toM. disparis limited so minimum inhibitory concentrations (MIC) of a range of antimicrobials routinely used in BRD were evaluated using a broth microdilution technique for 41M. disparisolates collected in Italy between 2011-2019. While all isolates had low MIC values for florfenicol (<1 mu g/mL), many showed high MIC values for erythromycin (MIC90 >= 8 mu g/mL). Tilmicosin MIC values were higher (MIC50 = 32 mu g/mL) than those for tylosin (MIC50 = 0.25 mu g/mL). Seven isolates had high MIC values for lincomycin, tilmicosin and tylosin (>= 32 mu g/mL). More, alarmingly, results showed more than half the strains had high MICs for enrofloxacin, a member of the fluoroquinolone class considered critically important in human health. A time-dependent progressive drift of enrofloxacin MICs towards high-concentration values was observed, indicative of an on-going selection process among the isolates.

Epidemiological and Clinical Characteristics of Patients With Coronavirus Disease-2019 in Shiyan City, China

FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY

Authors: Liu, Long; Lei, Xu; Xiao, Xiao; Yang, Jing; Li, Jian; Ji, Manshan; Du, Weixing; Tan, Huabing; Zhu, Jianyong; Li, Bei; Jin, Zhixiong; Liu, Weiyong; Wu, Jianguo; Liu, Zhixin

Abstract

To investigate the early epidemic of COVID-19, a total of 176 confirmed COVID-19 cases in Shiyan city, Hubei province, China were surveyed. Our data indicated that the rate of emergence of early confirmed COVID-19 cases in Hubei province outside Wuhan was dependent on migration population, and the second-generation of patients were family clusters originating from Wuhan travelers. Epidemiological investigation indicated that the reproductive number (R-0) under containment strategies was 1.81, and asymptomatic SARS-CoV-2 carriers were contagious with a transmission rate of 10.7%. Among the 176 patients, 53 were admitted to the Renmin Hospital of Hubei University of Medicine. The clinical characteristics of these 53 patients were collected and compared based on a positive RT-PCR test and presence of pneumonia. Clinical data showed that 47.2% (25/53) of COVID-19 patients were co-infected with Mycoplasma pneumoniae, and COVID-19 patients coinfected with M. pneumoniae had a higher percentage of monocytes (P < 0.0044) and a lower neutrophils percentage (P < 0.0264). Therefore, it is important to assess the transmissibility of infected asymptomatic individuals for SARS-CoV-2 transmission; moreover, clinicians should be alert to the high incidence of co-infection with M. pneumoniae in COVID-19 patients.