Specifications
Immunogen
UBE2L3 (AAH53368, 1 a.a. ~ 155 a.a) full length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Target
Alternative Names
ubiquitin-conjugating enzyme E2L 3; E2-F1; UBCH7; UbcM4; Ubiquitin carrier protein L3; ubiquitin-conjugating enzyme E2 L3; Ubiquitin-conjugating enzyme E2-F1; ubiquitin-conjugating enzyme UBCH7; Ubiquitin-protein ligase L3; UBCE7; L-UBC; EC 6.3.2.19; OTTH
Product Background
Antigen Description
The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes (E1s), ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s). This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is demonstrated to participate in the ubiquitination of p53, c-Fos, and the NF-kB precursor p105 in vitro. Several alternatively spliced transcript variants have been found for this gene.
Mouse monoclonal antibody raised against a full length recombinant UBE2L3.
Pathway
Adaptive Immunity Signaling, organism-specific biosystem; Alpha-synuclein signaling, organism-specific biosystem; Antigen processing: Ubiquitination & Proteasome degradation, organism-specific biosystem; BARD1 signaling events, organism-specific biosystem; Class I MHC mediated antigen processing & presentation, organism-specific biosystem; Immune System, organism-specific biosystem
Citations
Publication ()
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COA
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