Synthetic peptide: C-EFTKKYGEKRPVD, corresponding to C terminal amino acids 142/154 of Human Ube2L3
Conjugate
Unconjugated
Applications
Application Notes
ELISA: antibody detection limit dilution 1/128000. WB: Use at a concentration of 0.5 - 2 μg/ml. Detects a band of approximately 18 kDa (predicted molecular weight: 18 kDa).
Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes Lys-11-linked polyubiquitination. Involved in the selective degradation of short-lived and abnormal proteins. Down-regulated during the S-phase it is involved in progression through the cell cycle. Regulates nuclear hormone receptors transcriptional activity. May play a role in myelopoiesis.
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