Human MSL3 peptide

Nature

Synthetic

Tag/Conjugate

Unconjugated

Format

Liquid

Preservative

None

Storage

Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.

Entrez Gene ID

Antigen Description

This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010]

Function

DNA binding; methylated histone residue binding; sequence-specific DNA binding transcription factor activity;

Synonyms

MSL3; male-specific lethal 3 homolog (Drosophila); MSL3L1; male-specific lethal 3 homolog; MSL3-like 1; male-specific lethal-3 protein-like 1;