Rabbit Anti-Human MSL3 (a.a. 225-521) Polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Human; Mouse; Rat

Immunogen

Recombinant human MSL3 protein; Source: E. coli derived, PGEX-4T; Tag: GST; Domain: 225-521 aa of BC031210

Conjugate

Application Notes

WB: 1:500-1:2000

General Notes

This product (Catalog No. CABT-BL5203) is a rabbit-derived polyclonal antibody raised against human MSL3, targeting the amino acid region 225–521 of the protein. This antibody exhibits cross-reactivity with Human MSL3 from mouse and rat. It has been affinity purified by Protein A. This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8. [provided by RefSeq, Jul 2010].
CABT-BL5203 is suitable for use in Western blot (WB) (1:500–1:2,000) application.
CABT-BL5203 is supplied as a liquid formulation in PBS with 0.02% sodium azide and 50% glycerol, pH 7.3. For long-term storage, keep at −20 °C. For short-term use, store at 2–8 °C. Avoid repeated freeze–thaw cycles to maintain antibody integrity and performance.

Alternative Names

Male specific lethal 3 homolog; MSL3; MSL3 like 1; MSL3L1

Entrez Gene ID

UniProt ID