Anti-MSL3 (full length) polyclonal antibody

Antibody Isotype

IgG

Species Reactivity

Mouse; Rat; Human

Immunogen

Full length Human MSL3L1 (AAH31210. 1, amino acids 1-521).

Conjugate

Application Notes

WB: 1μg/ml
ICC/IF: 10μg/ml

Alternative Names

MSL3; male-specific lethal 3 homolog (Drosophila); male specific lethal 3 like 1 (Drosophila) , male specific lethal 3 (Drosophila) like 1 , MSL3L1; male-specific lethal 3 homolog; AU018931; DKFZp586J1822; Drosophila MSL3 like 1; Male specific lethal 3 (Drosophila) like 1; Male specific lethal 3 homolog (Drosophila); Male specific lethal 3 homolog 1 (Drosophila); Male specific lethal 3 homolog 1; Male specific lethal 3 homolog; Male specific lethal 3 like 1 (Drosophila); Male specific lethal 3 like 1; Male specific lethal 3 protein like 1; MSL3 like 1; Msl31; MSL3L1; OTTHUMP00000022911; OTTHUMP00000022912; MSL3-like 1; male-specific lethal-3 protein-like 1; MSL3L1;

Entrez Gene ID

UniProt ID

Antigen Description

This gene encodes a nuclear protein that is similar to the product of the Drosophila male-specific lethal-3 gene. The Drosophila protein plays a critical role in a dosage-compensation pathway, which equalizes X-linked gene expression in males and females. Thus, the human protein is thought to play a similar function in chromatin remodeling and transcriptional regulation, and it has been found as part of a complex that is responsible for histone H4 lysine-16 acetylation. This gene can undergo X inactivation. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 2, 7 and 8.