L. monocytogenes Internalin [His] (DAG4326)

L. monocytogenes Internalin [His], recombinant protein from E. coli

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Summary
Documentation

Product Overview

Recombinant Listeria monocytogenes Internalin, His-tagged

Nature

Recombinant

Tag/Conjugate

His

Procedure

None

Purity

Greater than 95.0% as determined by SDS-PAGE.

Format

Internalin is lyophilized from a 0.2um filtered concentrated solution in 20mM PB pH7.4 and 300mM NaCl.

Preservative

None

Storage

2-8°C short term, -20°C long term

Introduction

Internalins are surface proteins found on Listeria monocytogenes. They exist in two known forms, InlA and InlB. They are used by the bacteria to invade mammalian cells via cadherins transmembrane proteins. The exact role of these proteins and their invasiveness in vivo is not completely understood. In cultured cells, InlA is necessary to facilitate Listeria entry into human epithelial cells. While InlB is necessary for Listeria internalisation in several other cell types, including hepatocytes, fibroblasts, and epithelioid cells.

Keywords

L. monocytogenes Internalin; Listeria Monocytogenes Internalin; Internalin; Listeria Monocytogenes; L. monocytogenes; Listeria; Listeria monocytogenes Internalin