L. monocytogenes Internalin [His] (DAG4326)
L. monocytogenes Internalin [His], recombinant protein from E. coli
DatasheetProduct Overview
Recombinant Listeria monocytogenes Internalin, His-tagged
Nature
Recombinant
Tag/Conjugate
His
Procedure
None
Purity
Greater than 95.0% as determined by SDS-PAGE.
Format
Internalin is lyophilized from a 0.2um filtered concentrated solution in 20mM PB pH7.4 and 300mM NaCl.
Preservative
None
Storage
2-8°C short term, -20°C long term
Introduction
Internalins are surface proteins found on Listeria monocytogenes. They exist in two known forms, InlA and InlB. They are used by the bacteria to invade mammalian cells via cadherins transmembrane proteins. The exact role of these proteins and their invasiveness in vivo is not completely understood. In cultured cells, InlA is necessary to facilitate Listeria entry into human epithelial cells. While InlB is necessary for Listeria internalisation in several other cell types, including hepatocytes, fibroblasts, and epithelioid cells.
Keywords
L. monocytogenes Internalin; Listeria Monocytogenes Internalin; Internalin; Listeria Monocytogenes; L. monocytogenes; Listeria; Listeria monocytogenes Internalin
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