Recombinant Listeria monocytogenes p60 [His]

Product Overview

A DNA sequence encoding Listeria monocytogenes p60 (aa 1-484) was expressed with a polyhistidine tag at the C-terminus.

Target

L. monocytogenes

Nature

Recombinant

Tag/Conjugate

His

Molecular Weight

50 kDa

Endotoxin

<1EU/ug

Purity

> 90 % as determined by SDS-PAGE

Format

Liquid

Concentration

0.5 mg/mL

Buffer

PBS, pH 7.2

Preservative

None

Storage

Store at -20°C

Introduction

Listeria monocytogenes is the species of pathogenic bacteria that causes the infection listeriosis. It is a facultative anaerobic bacterium, capable of surviving in the presence or absence of oxygen. It can grow and reproduce inside the host's cells and is one of the most virulent foodborne pathogens: 20 to 30% of foodborne listeriosis infections in high-risk individuals may be fatal. Responsible for an estimated 1,600 illnesses and 260 deaths in the United States annually, listeriosis ranks third in total number of deaths among foodborne bacterial pathogens, with fatality rates exceeding even Salmonella spp. and Clostridium botulinum. In the European Union, listeriosis follows an upward trend that began in 2008, causing 2,161 confirmed cases and 210 reported deaths in 2014, 16% more than in 2013. Listeriosis mortality rates are also higher in the EU than for other foodborne pathogens.

Keywords

Listeria monocytogenes; p60; iap