Product Overview
IkBa ( C - term ) peptide ( human )
Tag/Conjugate
Unconjugated
Buffer
Preservative: 0.01% Sodium Azide; Constituents: 0.15M Sodium Chloride, 0.02M Potassium Phosphate. pH 7.2
Preservative
0.01% Sodium Azide
Storage
Keep as concentrated solution. Store at 4℃ short term. For extended storage aliquot and store at -20℃ or below. Avoid freeze-thaw cycles.
Antigen Description
This gene encodes a member of the NF-kappa-B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF-kappa-B/REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1-mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T-cell immunodeficiency autosomal dominant disease. [provided by RefSeq, Aug 2011]
Function
NF-kappaB binding; NF-kappaB binding; enzyme binding; heat shock protein binding; identical protein binding; nuclear localization sequence binding; protein binding; protein complex binding; transcription factor binding; ubiquitin protein ligase binding;
Synonyms
NFKBIA; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha; IKBA; MAD-3; NFKBI; NF-kappa-B inhibitor alpha; ikB-alpha; IkappaBalpha; I-kappa-B-alpha; nuclear factor of kappa light chain gene enhancer in B-cells; major histocompatibility complex enhancer-binding protein MAD3;
Datasheet