HIV type 1 P15 (DAG-P2235)

HIV type 1 P15 (aa 1 - 527), recombinant protein from Wheat Datasheet

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Product Overview
HIV1 p15 protein
Nature
Recombinant
Tag/Conjugate
Unconjugated
Molecular Weight
14 kDa
Cellular Localization
Cytoplasmic and Nuclear
Bio-activity
HIV1 p15 protein can be used as a substrate for HIV1 protease in the presence of HIV1 genomic RNA; in studies of structure and function of AIDS virus as precursor of nucleocapsid p7 protein that binds to HIV1 genome RNA; as p15 antigen in detection of ant
Purity
> 90 % by SDS-PAGE.This antigen is highly purified by several steps of chromatography.
Format
Liquid
Buffer
pH: 7.50Constituents: 0.078% Beta mercaptoethanol, 0.32% Tris HCl, 50% Glycerol, 0.29% Sodium chloride
Storage
Shipped at 4°C. Store at -20oC. pH: 7.50Constituents: 0.078% Beta mercaptoethanol, 0.32% Tris HCl, 50% Glycerol, 0.29% Sodium chloride
Introduction
The human immunodeficiency virus (HIV) is a lentivirus (slowly replicating retrovirus) that causes the acquired immunodeficiency syndrome (AIDS), a condition in humans in which progressive failure of the immune system allows life-threatening opportunistic
Antigen Description
HIV1 p15(Gag) and its protease cleavage products, nucleocapsid protein p7 and p6, are believed to play a major role in viral infectivity and assembly during the early and late stages of retroviral life cycle. p15 is frequently recognized by HIV1-specific CD8+T cells in natural HIV1 infection and may be an important target for the design of future HIV1 vaccines.
Keywords
gag; Gag polyprotein; Human Immunodeficiency virus 1; Nucleocapsid protein p7; p15; p6 gag; Pr55Gag; HIV1 p15

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