Product Overview
C-terminal 6xHis tagged HIV-1/clade C p24 protein
Alternative Names
Human Immunodeficiency Virus; HIV p24; HIV; HIV-1 p24; HIV-1; HIV type 1 p24
Storage
After reconstitution, stable for a month at 4?C. For long term storage, split it into small aliquots and keep at -80°C. Avoid repeated freezing and thawing.
Introduction
p24 is a component of the HIV particle capsid. There are approximately 2000 molecules per virus particle, or at a molecule weight of 24 kDa, about 10^4 virus particles per picogram of p24. The onset of symptoms of AIDS correlates with a reduction in the number of CD4+ T-cells and increased levels of virus and p24 in the blood. It is a component of the gag polyprotein.
Keywords
Human Immunodeficiency Virus; HIV p24; HIV; HIV-1 p24; HIV-1; HIV type 1 p24
Citations
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Flamar, A; Le Grand, R; et al. Targeting HIV Gag p24 to DICR on dendritic cells induces T cell and potent and long-lasting antibody responses in non-human primates. RETROVIROLOGY 9:-(2012).
Manlutac, ALM; Giesick, JS; et al. Identification of early HIV infections using the fourth generation Abbott ARCHITECT HIV Ag/Ab Combo chemiluminescent microparticle immunoassay (CIA) in San Diego County. JOURNAL OF CLINICAL VIROLOGY 58:E44-E47(2013).