Recombinant (HIV-1) Nef biotin-conjugated. HIV-1 Nef is a 27kDa protein abundantly produced shortly after virus infection. Nef is an essential factor for efficient viral replication and pathogenesis, it also facilitates virus replication and enhances viri
Nature
Recombinant
Tag/Conjugate
Biotin
Molecular Weight
27 kDa
Alternative Names
Human Immunodeficiency Virus; HIV Nef; HIV; HIV-1 Nef; HIV-1; HIV type 1 Nef
Purity
> 90% pure estimated by SDS-PAGE (EU Ph. 5.0 § 2.5.31)
Format
Liquid
Buffer
1X PBS, 0.05%(v/v) glycerol
Preservative
None
Storage
Shipped at -20°C. The protein is stable for 12 months if stored at -20°C. Avoid freeze-thaw cycles.
Introduction
Nef is a multifunctional protein of 27 kDa in HIV1 and 35 kDa in HIV2. It induces the endocytosis of CD4 Receptor and reduces the MHC1 Receptors. Thereby it enhances viral infectivity and affects T-cell signalling.
Keywords
Human Immunodeficiency Virus; HIV Nef; HIV; HIV-1 Nef; HIV-1; HIV type 1 Nef
Citations
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