Human FGR blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-FGR antibody

Target

FGR

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

This gene is a member of the Src family of protein tyrosine kinases (PTKs). The encoded protein contains N-terminal sites for myristylation and palmitylation, a PTK domain, and SH2 and SH3 domains which are involved in mediating protein-protein interactions with phosphotyrosine-containing and proline-rich motifs, respectively. The protein localizes to plasma membrane ruffles, and functions as a negative regulator of cell migration and adhesion triggered by the beta-2 integrin signal transduction pathway. Infection with Epstein-Barr virus results in the overexpression of this gene. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Function

ATP binding; Fc-gamma receptor I complex binding; immunoglobulin receptor binding; immunoglobulin receptor binding; non-membrane spanning protein tyrosine kinase activity; non-membrane spanning protein tyrosine kinase activity; nucleotide binding; phospho

Synonyms

FGR; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; SRC2; tyrosine-protein kinase Fgr; c fgr; p55c fgr; p55-c-fgr protein; c-fgr protooncogene; proto-oncogene c-Fgr; c-src-2 proto-oncogene; proto-oncogene tyrosine-protein kinase FGR; c-fgr; c-src2; p55-Fgr; p58-Fgr; p55c-fgr; p58c-fgr; FLJ43153; MGC75096;