Specifications
Species Reactivity
Mouse; Human
Immunogen
Purified recombinant fragment of human FGR expressed in E. Coli.
Applications
Application Notes
WB: 1/500 - 1/2000; ELISA: 1/10000;
Target
Alternative Names
FGR; Gardner-Rasheed feline sarcoma viral (v-fgr) oncogene homolog; SRC2; tyrosine-protein kinase Fgr; c fgr; p55c fgr; p55-c-fgr protein; c-fgr protooncogene; proto-oncogene c-Fgr; c-src-2 proto-oncogene; proto-oncogene tyrosine-protein kinase FGR; c-fgr
Product Background
Antigen Description
Fgr is a member of the Src family of non-receptor tyrosine kinases. It is expressed in neutrophils, monocytes, macrophages and natural killer cells. Expression of Fgr is developmentally regulated and required in normal myelomonocytic differentiation in vivo. HL-60 cells induced to differentiate with retinoic acid express high levels of Fgr.
Pathway
Alpha-synuclein signaling, organism-specific biosystem; CXCR4-mediated signaling events, organism-specific biosystem; Chemokine signaling pathway, organism-specific biosystem; Chemokine signaling pathway, conserved biosystem; Class I PI3K signaling events, organism-specific biosystem; EPHA forward signaling, organism-specific biosystem; Ephrin B reverse signaling, organism-specific biosystem;
Citations
Publication ()
Have you cited DCABH-10008 in a publication?
Let us know and earn a reward for your research.
COA
Loading ......
