Human FANCM blocking peptide

Product Overview

Blocking/Immunizing peptide for anti-FANCM antibody

Target

FANCM

Nature

Synthetic

Tag/Conjugate

Unconjugated

Application Notes

For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.

Format

Lyophilized powder

Preservative

None

Storage

Shipped at ambient temperature, store at -20°C.

Entrez Gene ID

Antigen Description

The Fanconi anemia complementation group (FANC) currently includes FANCA, FANCB, FANCC, FANCD1 (also called BRCA2), FANCD2, FANCE, FANCF, FANCG, FANCI, FANCJ (also called BRIP1), FANCL, FANCM and FANCN (also called PALB2). The previously defined group FANCH is the same as FANCA. Fanconi anemia is a genetically heterogeneous recessive disorder characterized by cytogenetic instability, hypersensitivity to DNA crosslinking agents, increased chromosomal breakage, and defective DNA repair. The members of the Fanconi anemia complementation group do not share sequence similarity; they are related by their assembly into a common nuclear protein complex. This gene encodes the protein for complementation group M.

Function

ATP binding; ATP-dependent helicase activity; DNA binding; chromatin binding; helicase activity; hydrolase activity; nuclease activity; nucleotide binding; protein binding;

Synonyms

FANCM; Fanconi anemia, complementation group M; KIAA1596; Fanconi anemia group M protein; FAAP250; protein Hef ortholog; ATP-dependent RNA helicase FANCM; fanconi anemia-associated polypeptide of 250 kDa; MGC176453;