This gene encodes a member of the cytoplasmic polyadenylation element binding protein family. This highly conserved protein binds to a specific RNA sequence, called the cytoplasmic polyadenylation element, found in the 3' untranslated region of some mRNAs. The encoded protein functions in both the cytoplasm and the nucleus. It is involved in the regulation of mRNA translation, as well as processing of the 3' untranslated region, and may play a role in cell proliferation and tumorigenesis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014]
Function
mRNA 3'-UTR AU-rich region binding; metal ion binding; nucleotide binding; translation repressor activity, nucleic acid binding
Synonyms
CPEB1; cytoplasmic polyadenylation element binding protein 1; CEBP; CPEB; CPEB-1; CPE-BP1; hCPEB-1; cytoplasmic polyadenylation element-binding protein 1; CPE-binding protein 1
Citations
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