Tag/Conjugate
Unconjugated
SequenceSimilarities
SETDB2 peptide is a 15 amino acid synthetic peptide near the C or N-Terminus of SETDB2.
Purity
> 95 % by SDS-PAGE.
Storage
Shipped at 4°C. Upon delivery aliquot and store at -20°C or -80°C. Avoid repeated freeze / thaw cycles. Information available upon request.
Reconstitution
SETDB2 peptide is supplied as 1mg of dried peptide. When the peptide is reconstituted in 1 mL strile water, the concentration will be 1 mg/mL.
Introduction
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM, Mar 2008]
Synonyms
SETDB2; SET domain, bifurcated 2; CLLD8; CLLL8; KMT1F; C13orf4; histone-lysine N-methyltransferase SETDB2; lysine N-methyltransferase 1F; chronic lymphocytic leukemia deletion region 8; chronic lymphocytic leukemia deletion region gene 8 protein;
Citations
Publication ()
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COA
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