Product Overview
Blocking/Immunizing peptide for anti-CLLD8/SETDB2 antibody
Tag/Conjugate
Unconjugated
Application Notes
For in vitro research use only. Not intended for any diagnostic or therapeutic purpose. Not for human or animal consumption.
Format
Lyophilized powder
Storage
Shipped at ambient temperature, store at -20°C.
Antigen Description
Proteins that contain a SET domain, such as SETDB2, modulate gene expression epigenetically through histone H3 (see MIM 601128) methylation. SETDB2 is likely a histone H3 methyltransferase, as it contains both the active site and flanking cysteine residues required for catalytic activity (Zhang et al., 2003 [PubMed 12754510]).[supplied by OMIM, Mar 2008]
Function
DNA binding; histone methyltransferase activity (H3-K9 specific); metal ion binding; methyltransferase activity; transferase activity; zinc ion binding;
Synonyms
SETDB2; SET domain, bifurcated 2; C13orf4, chromosome 13 open reading frame 4; histone-lysine N-methyltransferase SETDB2; CLLD8; CLLL8; KMT1F; lysine N-methyltransferase 1F; chronic lymphocytic leukemia deletion region 8; chronic lymphocytic leukemia deletion region gene 8 protein; C13orf4; DKFZp586I0123; DKFZp761J1217;
Citations
Publication ()
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COA
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